Date of Thesis

2010

Description

This study uses a molecular technique called MARCM (Mosaic Analysis with a Repressible Cell Marker) to label neuronal lineages that overexpress the Hox gene Ultrabithorax (Ubx) in an unlabeled, wild type background. The results indicate that the overexpression of Ubx is sufficient to transform more anterior neuronal lineages to themorphology of their more posterior counterparts. The data presented here begin to elucidate the role that the Hox genes have in shaping segment-specific neural connections in the post-embryonic ventral nervous system.

Keywords

ventral nervous system development, Drosophila, hox genes, neuronal segment patterning

Access Type

Masters Thesis

Degree Type

Master of Science

Major

Biology

First Advisor

Elizabeth C. Marin

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