The Pre-Metaphase Stretch: a Re-Examination
Pre-metaphase stretch is a term first coined by the preeminent cell biologist Sally Hughes-Schrader in 1950 to describe an elongation of prometaphase chromosomes observed in the primary spermatocytes of phasmid insects and praying mantids. Research from many groups since Hughes- Schrader’s initial observation has revealed reasons for both how and why chromosomes might elongate prior to metaphase. In this review, we describe Hughes-Schrader’s initial findings and discuss how recent work illuminates and provides some mechanistic explanation for this long-ago observed phenomenon.
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Czekalski, Megan A. and Paliulis, Leocadia V.. "The Pre-Metaphase Stretch: a Re-Examination." (2021) : 3-12.