The Pre-Metaphase Stretch: a Re-Examination

Publication Date

6-29-2021

Description

Pre-metaphase stretch is a term first coined by the preeminent cell biologist Sally Hughes-Schrader in 1950 to describe an elongation of prometaphase chromosomes observed in the primary spermatocytes of phasmid insects and praying mantids. Research from many groups since Hughes- Schrader’s initial observation has revealed reasons for both how and why chromosomes might elongate prior to metaphase. In this review, we describe Hughes-Schrader’s initial findings and discuss how recent work illuminates and provides some mechanistic explanation for this long-ago observed phenomenon.

Journal

DNA

Volume

1

Issue

1

First Page

3

Last Page

12

Department

Biology

Open Access

Link to OA full text

DOI

10.3390/dna1010002

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