A review of tethers: elastic connections between separating partner chromosomes in anaphase

Publication Date

2018

Description

Recent work has demonstrated the existence of elastic connections, or tethers, between the telomeres of separating partner chromosomes in anaphase. These tethers oppose the poleward spindle forces in anaphase. Functional evidence for tethers has been found in a wide range of animal taxa, suggesting that they might be present in all dividing cells. An examination of the literature on cell division from the nineteenth century to the present reveals that connections between separating partner chromosomes in anaphase have been described in some of the earliest observations of cell division. Here, we review what is currently known about connections between separating partner chromosomes in anaphase, and we speculate on possible functions of tethers, and on what they are made of and how one might determine their composition.

Journal

Protoplasma

Volume

255

Issue

3

First Page

733

Last Page

740

Department

Biology

DOI

10.1007/s00709-017-1201-1

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