Date of Thesis

2011

Description

To determine the subcellular localization of the tegument proteins pp65, pp71, pp150, and pp28 as fusions to one of several fluorescent proteins. Since these tegument proteins play pivotal roles in several stages of the viral life cycle, knowledge of where and the mechanism of how these proteins localize upon release could result in a better understanding of their function during a lytic infection as well as assist in the development of an effective, novel antiviral treatment.

Keywords

human cytomegalovirus, HCMV, virology, tegument, pp65, pp71, pp150, pp28, transfection, confocal microscopy, molecular biology

Access Type

Honors Thesis

Major

Biology

First Advisor

Marie Pizzorno

Comments

PUBLIC

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